Title : Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization.

Pub. Date : 2004 Sep 22

PMID : 15385613






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Capsaicin and NGF induce phosphorylation of the PI3K downstream target AKT (protein kinase B), which is blocked by the PI3K inhibitors LY294002 and wortmannin, indicative of the activation of PI3K by both agents. Capsaicin AKT serine/threonine kinase 1 Rattus norvegicus