Title : Progesterone and allopregnanolone reduce inflammatory cytokines after traumatic brain injury.

Pub. Date : 2004 Oct

PMID : 15380490






2 Functional Relationships(s)
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1 This study examined the changes in expression of the proinflammatory cytokines IL-1beta and TNF-alpha after progesterone (8 mg/kg) or allopregnanolone (4 mg/kg) treatment in brain-injured rats at 3, 8, and 12 h and 6 days post-injury. Progesterone interleukin 1 beta Rattus norvegicus
2 The results indicated that progesterone and allopregnanolone reduce both IL-1beta and TNF-alpha at 3 h post-injury, when the expression of these cytokines peaks. Progesterone interleukin 1 beta Rattus norvegicus