Title : Hydrogen sulfide-induced apoptosis of human aorta smooth muscle cells via the activation of mitogen-activated protein kinases and caspase-3.

Pub. Date : 2004 Nov

PMID : 15371330






4 Functional Relationships(s)
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Protein Name
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1 Suppression of extracellular signal-regulated kinase (ERK) activity, but not of p38 activity, inhibited the H2S-induced apoptosis of HASMCs. hasmcs mitogen-activated protein kinase 1 Homo sapiens
2 Suppression of extracellular signal-regulated kinase (ERK) activity, but not of p38 activity, inhibited the H2S-induced apoptosis of HASMCs. hasmcs mitogen-activated protein kinase 1 Homo sapiens
3 The activation of ERK by H2S in HASMCs was accompanied by increased caspase-3 activity. hasmcs mitogen-activated protein kinase 1 Homo sapiens
4 Of the three investigated MAPKs, only ERK played an active role in mediating H2S-induced apoptosis of HASMCs by activating caspase-3. hasmcs mitogen-activated protein kinase 1 Homo sapiens