Title : Sophorae radix extract inhibits high glucose-induced vascular cell adhesion molecule-1 up-regulation on endothelial cell line.

Pub. Date : 2004 Oct

PMID : 15369739






3 Functional Relationships(s)
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Protein Name
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1 Sophorae radix extract inhibits high glucose-induced vascular cell adhesion molecule-1 up-regulation on endothelial cell line. Glucose vascular cell adhesion molecule 1 Homo sapiens
2 RESULTS: SR extract significantly inhibited high glucose-induced expression of VCAM-1 in a dose-dependent manner and reduced the level of VCAM-1 mRNA through interfering with translocation of nuclear factor-kappaB (NF-kappaB). Glucose vascular cell adhesion molecule 1 Homo sapiens
3 Decreased VCAM-1 expression by SR extract was associated reduction of adherence between high glucose-stimulated ECV304 cells and human monocyte-like HL-60 cells. Glucose vascular cell adhesion molecule 1 Homo sapiens