Pub. Date : 2004 Oct 1
PMID : 15345328
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GABA(A)/central benzodiazepine receptor and peripheral benzodiazepine receptor ligands as inducers of phenobarbital-inducible CYP2B and CYP3A. | Phenobarbital | translocator protein | Rattus norvegicus |
| 2 | While no nuclear receptor for which PB is an agonist ligand has yet been identified, PB is a ligand of GABA(A) receptors and it can displace [(3)H] 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide (PK 11195) from its binding site on the peripheral benzodiazepine receptor (PBR). | Phenobarbital | translocator protein | Rattus norvegicus |
| 3 | While no nuclear receptor for which PB is an agonist ligand has yet been identified, PB is a ligand of GABA(A) receptors and it can displace [(3)H] 1-(2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide (PK 11195) from its binding site on the peripheral benzodiazepine receptor (PBR). | Phenobarbital | translocator protein | Rattus norvegicus |