Title : The ADPRT V762A genetic variant contributes to prostate cancer susceptibility and deficient enzyme function.

Pub. Date : 2004 Sep 1

PMID : 15342424






4 Functional Relationships(s)
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Protein Name
Organism
1 The second study used freshly isolated peripheral lymphocytes from 354 cancer-free subjects to demonstrate that the ADPRT 762 A allele contributed to significantly lower adenosine diphosphate ribosyl transferase (ADPRT)/PARP-1 activities in response to H2O2 in a gene dosage-dependent manner (P < 0.0001, test for linear trend). Hydrogen Peroxide poly(ADP-ribose) polymerase 1 Homo sapiens
2 The second study used freshly isolated peripheral lymphocytes from 354 cancer-free subjects to demonstrate that the ADPRT 762 A allele contributed to significantly lower adenosine diphosphate ribosyl transferase (ADPRT)/PARP-1 activities in response to H2O2 in a gene dosage-dependent manner (P < 0.0001, test for linear trend). Hydrogen Peroxide poly(ADP-ribose) polymerase 1 Homo sapiens
3 The second study used freshly isolated peripheral lymphocytes from 354 cancer-free subjects to demonstrate that the ADPRT 762 A allele contributed to significantly lower adenosine diphosphate ribosyl transferase (ADPRT)/PARP-1 activities in response to H2O2 in a gene dosage-dependent manner (P < 0.0001, test for linear trend). Hydrogen Peroxide poly(ADP-ribose) polymerase 1 Homo sapiens
4 The second study used freshly isolated peripheral lymphocytes from 354 cancer-free subjects to demonstrate that the ADPRT 762 A allele contributed to significantly lower adenosine diphosphate ribosyl transferase (ADPRT)/PARP-1 activities in response to H2O2 in a gene dosage-dependent manner (P < 0.0001, test for linear trend). Hydrogen Peroxide poly(ADP-ribose) polymerase 1 Homo sapiens