Title : Intracellular kinetics of iron in reticulocytes: evidence for endosome involvement in iron targeting to mitochondria.

Pub. Date : 2005 Jan 1

PMID : 15331447






2 Functional Relationships(s)
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1 Importantly, both the myosin light chain kinase inhibitor wortmannin and the calmodulin antagonist, N-(6-aminohexyl)-5-chloro-1-naphthalene-sulfonamide (W-7), caused significant inhibition of 59Fe incorporation from 59Fe-Tf-labeled endosomes into heme, suggesting that myosin is required for Tf-vesicle movement. W 7 calmodulin 1 Homo sapiens
2 Importantly, both the myosin light chain kinase inhibitor wortmannin and the calmodulin antagonist, N-(6-aminohexyl)-5-chloro-1-naphthalene-sulfonamide (W-7), caused significant inhibition of 59Fe incorporation from 59Fe-Tf-labeled endosomes into heme, suggesting that myosin is required for Tf-vesicle movement. W 7 calmodulin 1 Homo sapiens