Title : The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.

Pub. Date : 2004 Aug 31

PMID : 15326314






1 Functional Relationships(s)
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1 The detection of 3-chlorotyrosine in HDL isolated from vascular lesions raises the possibility that MPO, by virtue of its ability to form HOCl, may promote atherogenesis by counteracting the established antiatherogenic effects of HDL and the ATP-binding cassette transporter A1 pathway. 3-chlorotyrosine myeloperoxidase Homo sapiens