Title : Microtubule disruption inhibits autophagosome-lysosome fusion: implications for studying the roles of aggresomes in polyglutamine diseases.

Pub. Date : 2004 Dec

PMID : 15325591






1 Functional Relationships(s)
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1 Two recent studies used microtubule disruption with nocodazole to inhibit aggresome formation and observed increased toxicity of expanded polyglutamines in the context of huntingtin exon 1 and a truncated androgen receptor. polyglutamine androgen receptor Rattus norvegicus