Pub. Date : 2005 Feb
PMID : 15316930
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Moreover, HL60 cell resistance to 2.5 microM As2O3 could be significantly reduced by incubation with SN50, a peptide inhibitor selective for the NF-kappaB transcription factor. | Arsenic Trioxide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | Taken together our findings suggest that a constitutive activation of the PI3K/Akt pathway, which is increasingly detected in some types of acute myeloid leukemia, may contribute to As2O3 resistance, most likely through NF-kappaB activation. | Arsenic Trioxide | nuclear factor kappa B subunit 1 | Homo sapiens |