Pub. Date : 1992 Feb 25
PMID : 1531616
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Neocarzinostatin-mediated DNA damage in a model AGT.ACT site: mechanistic studies of thiol-sensitive partitioning of C4" DNA damage products. | Sulfhydryl Compounds | angiotensinogen | Homo sapiens |
| 2 | Structure-function studies revealed that a variety of different thiols produced bistranded lesions in this model by predominantly C4"-hydrogen atom abstraction (84-93%) at the T of AGT and C5"-hydrogen atom abstraction (87-91%) at the T of ACT. | Sulfhydryl Compounds | angiotensinogen | Homo sapiens |
| 3 | Production of 3"-phosphoglycolate residues, restricted mainly to the T of AGT in bistranded lesions, correlated with the incidence of direct DS breaks in the AGT.ACT model and in plasmid DNA and appeared to be influenced by the reducing power of the thiol activator. | Sulfhydryl Compounds | angiotensinogen | Homo sapiens |