Title : Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway.

Pub. Date : 2004 Oct 8

PMID : 15304489






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Treatment with U0126, which inhibits ERK1/2 activation, reduced IGF-1-stimulated RUNX2 DNA binding without affecting RUNX2 protein levels. U 0126 RUNX family transcription factor 2 Homo sapiens
2 Treatment with U0126, which inhibits ERK1/2 activation, reduced IGF-1-stimulated RUNX2 DNA binding without affecting RUNX2 protein levels. U 0126 RUNX family transcription factor 2 Homo sapiens