Title : A combination of selective COX-2 inhibitors and hydrogen peroxide increase the reactive oxygen species formation in osteosarcoma cells after X-ray irradiation.

Pub. Date : 2004 Sep

PMID : 15289892






2 Functional Relationships(s)
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1 A combination of selective COX-2 inhibitors and hydrogen peroxide increase the reactive oxygen species formation in osteosarcoma cells after X-ray irradiation. Reactive Oxygen Species mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 A low dose concentration of COX-2 inhibitor in combination with hydrogen peroxide and irradiation did affect ROS formation in the intracellular compartment; however, this same combination of agents at high doses did not modulate the effect of irradiation. Reactive Oxygen Species mitochondrially encoded cytochrome c oxidase II Homo sapiens