Title : Genetic polymorphisms in cytochrome P450 enzymes: effect on efficacy and tolerability of HMG-CoA reductase inhibitors.

Pub. Date : 2004

PMID : 15285699






2 Functional Relationships(s)
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1 Apart from pravastatin and rosuvastatin, HMG-CoA reductase inhibitors are metabolized by the phase I cytochrome P450 (CYP) superfamily of drug metabolizing enzymes. Pravastatin cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Apart from pravastatin and rosuvastatin, HMG-CoA reductase inhibitors are metabolized by the phase I cytochrome P450 (CYP) superfamily of drug metabolizing enzymes. Pravastatin cytochrome P450 family 4 subfamily F member 3 Homo sapiens