Title : Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes.

Pub. Date : 2004 Jun 30

PMID : 15272234






1 Functional Relationships(s)
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1 In addition, the induction of COX-2 and MMP-2 was inhibited by the pretreatment of chondrocytes with a SB203580 or Ro 31-8220, indicating the involvement of protein kinase C (PKC) or p38 mitogen-activated protein kinase (MAPK). SB 203580 mitochondrially encoded cytochrome c oxidase II Homo sapiens