Title : Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling.

Pub. Date : 2004 Aug

PMID : 15266025






1 Functional Relationships(s)
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1 NHTBE cells expressed all four E-prostanoid (EP) receptor subtypes and misoprostol, an EP2 and EP4 agonist, increased MUC5AC production, whereas sulprostone, an EP1 and EP3 agonist, did not. Misoprostol prostaglandin E receptor 2 Homo sapiens