Title : The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones.

Pub. Date : 2004 Aug 16

PMID : 15261284






1 Functional Relationships(s)
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1 Many of these compounds show low nanomolar activity against lipopolysaccaride (LPS)-induced TNF-alpha production in THP-1 cells. lipopolysaccaride tumor necrosis factor Homo sapiens