Title : Role of mitochondrial phospholipid hydroperoxide glutathione peroxidase (PHGPx) as an antiapoptotic factor.

Pub. Date : 2004 Jul

PMID : 15256721






3 Functional Relationships(s)
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Protein Name
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1 Phospholipid hydroperoxide glutathione peroxidase (PHGPx) is a unique antioxidant enzyme that markedly reduces lipid hydroperoxide generated in biomembranes. Lipid Peroxides glutathione peroxidase 4 Homo sapiens
2 From studies of the overexpression of PHGPx, the generation of hydrogen peroxide and lipid hydroperoxide in mitochondria might be important triggers of apoptosis. Lipid Peroxides glutathione peroxidase 4 Homo sapiens
3 c</protein-id> liberation from mitochondria in 2DG-induced apoptosis since lipid hydroperoxide is a primary substrate for PHGPx. Lipid Peroxides glutathione peroxidase 4 Homo sapiens