Title : Adrenergic modulation of survival and cellular immune functions during polymicrobial sepsis.

Pub. Date : 2004

PMID : 15249727






3 Functional Relationships(s)
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1 Treatment with propranolol augmented the epinephrine-induced increase of splenocyte apoptosis, did not affect the decrease of splenocyte proliferation and IL-2 release, augmented the release of IL-6 and antagonized the mobilization of natural killer cells observed in epinephrine-treated animals. Propranolol interleukin 6 Mus musculus
2 Coadministration of propranolol and epinephrine augmented the propranolol-induced changes of splenocyte apoptosis and IL-6 release and was associated with the highest mortality of septic mice. Propranolol interleukin 6 Mus musculus
3 Coadministration of propranolol and epinephrine augmented the propranolol-induced changes of splenocyte apoptosis and IL-6 release and was associated with the highest mortality of septic mice. Propranolol interleukin 6 Mus musculus