Title : Cytochrome P450 pharmacogenetics as a predictor of toxicity and clinical response to pulse cyclophosphamide in lupus nephritis.

Pub. Date : 2004 Jul

PMID : 15248218






4 Functional Relationships(s)
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1 Cytochrome P450 pharmacogenetics as a predictor of toxicity and clinical response to pulse cyclophosphamide in lupus nephritis. Cyclophosphamide cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 Cyclophosphamide is a prodrug that requires activation by cytochrome P450 (CYP) enzymes. Cyclophosphamide cytochrome P450 family 4 subfamily F member 3 Homo sapiens
3 Cyclophosphamide is a prodrug that requires activation by cytochrome P450 (CYP) enzymes. Cyclophosphamide cytochrome P450 family 4 subfamily F member 3 Homo sapiens
4 CONCLUSION: Determination of selected cytochrome P450 enzyme genotypes may be valuable for predicting the risk of premature ovarian failure in lupus nephritis patients treated with cyclophosphamide. Cyclophosphamide cytochrome P450 family 4 subfamily F member 3 Homo sapiens