Title : Oscillatory shear stress upregulation of endothelial nitric oxide synthase requires intracellular hydrogen peroxide and CaMKII.

Pub. Date : 2004 Jul

PMID : 15242742






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Oscillatory shear stress upregulation of endothelial nitric oxide synthase requires intracellular hydrogen peroxide and CaMKII. Hydrogen Peroxide nitric oxide synthase 3 Bos taurus
2 We have previously shown that hydrogen peroxide (H(2)O(2)) upregulates endothelial nitric oxide synthase (eNOS) expression via a calcium/calmodulin-dependent protein kinase II (CaMKII)-mediated mechanism whereas it also acutely activates eNOS enzyme. Hydrogen Peroxide nitric oxide synthase 3 Bos taurus
3 We have previously shown that hydrogen peroxide (H(2)O(2)) upregulates endothelial nitric oxide synthase (eNOS) expression via a calcium/calmodulin-dependent protein kinase II (CaMKII)-mediated mechanism whereas it also acutely activates eNOS enzyme. Hydrogen Peroxide nitric oxide synthase 3 Bos taurus