Title : Potentiation of heroin and methadone hepatotoxicity by ethanol: an in vitro study using cultured human hepatocytes.

Pub. Date : 1992 Apr

PMID : 1523868






1 Functional Relationships(s)
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1 The increase in toxicity of heroin and methadone produced by ethanol is concomitant with a 40% increase in cytochrome P-450 levels of the pretreated hepatocytes. Ethanol cytochrome P450 family 4 subfamily F member 3 Homo sapiens