Title : Activation of trigeminal nociceptive neurons by parotid PAR-2 activation in rats.

Pub. Date : 2004 Jul 19

PMID : 15232294






2 Functional Relationships(s)
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1 Either the PAR-2 agonist SLIGRL-NH2 or capsaicin, injected into the parotid duct, caused expression of Fos in the trigeminal subnucleus caudalis, although the PAR-2-inactive reversed peptide had no such effect. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus
2 The Fos expression caused by PAR-2 activation was inhibited by ablation of capsaicin-sensitive sensory neurons. Capsaicin Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus