Title : Down-regulated expression of A disintegrin and metalloproteinase with thrombospondin-like repeats-1 by progesterone receptor antagonist is associated with impaired expansion of porcine cumulus-oocyte complexes.

Pub. Date : 2004 Oct

PMID : 15231699






1 Functional Relationships(s)
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1 These results suggest that the expression and induction of ADAMTS-1 through receptor-mediated action of progesterone in cumulus cells is one of the essential requirements for gonadotropin-regulated cumulus expansion of porcine COCs. Progesterone ADAM metallopeptidase with thrombospondin type 1 motif 1 Homo sapiens