Pub. Date : 2004 Jul
PMID : 15218361
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Growth and EGFR regulation in breast cancer cells by vitamin D and retinoid compounds. | Vitamin D | epidermal growth factor receptor | Homo sapiens |
| 2 | Transfection of an EGFR promoter containing reporter plasmid demonstrated vitamin D induced changes in reporter gene activity that paralleled the changes observed in EGFR mRNA and protein. | Vitamin D | epidermal growth factor receptor | Homo sapiens |
| 3 | Transfection of an EGFR promoter containing reporter plasmid demonstrated vitamin D induced changes in reporter gene activity that paralleled the changes observed in EGFR mRNA and protein. | Vitamin D | epidermal growth factor receptor | Homo sapiens |
| 4 | Electrophoretic mobility shift assays using a putative vitamin D response element within this region of the EGFR promoter demonstrated specific VDR binding. | Vitamin D | epidermal growth factor receptor | Homo sapiens |
| 5 | These results indicate that the vitamin D effect on EGFR expression in breast cancer cells has a transcriptional component likely mediated through a vitamin D responsive promoter sequence. | Vitamin D | epidermal growth factor receptor | Homo sapiens |
| 6 | These results indicate that the vitamin D effect on EGFR expression in breast cancer cells has a transcriptional component likely mediated through a vitamin D responsive promoter sequence. | Vitamin D | epidermal growth factor receptor | Homo sapiens |
| 7 | They also suggest that growth inhibition and EGFR down-regulation by vitamin D and retinoids may be related events in some breast cancer cells, but not in all. | Vitamin D | epidermal growth factor receptor | Homo sapiens |