Pub. Date : 2004 Oct 15
PMID : 15217838
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Nuclear translocation of p53 after fludarabine treatment was decreased when STAT1beta was overexpressed, and it was increased when STAT1alpha was induced. | fludarabine | tumor protein p53 | Homo sapiens |
2 | Our results show that imbalance between the antiproliferative/proapoptotic isoform STAT1alpha and the proliferative isoform STAT1beta is likely to play a crucial role in the regulation of proliferation and apoptosis and that STAT1alpha may regulate p53 activity and sensitize B cells to fludarabine-induced apoptosis. | fludarabine | tumor protein p53 | Homo sapiens |