Title : Molecular recognition properties of FN3 monobodies that bind the Src SH3 domain.

Pub. Date : 2004 Jun

PMID : 15217616






2 Functional Relationships(s)
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1 Five of these contained proline-rich sequences in their FG loop that resembled class I (i.e., +xxPxxP) peptide ligands for the Src SH3 domain. Proline SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens
2 The sixth clone lacked the proline-rich sequence and showed particularly high binding specificity to the Src SH3 domain among various SH3 domains tested. Proline SRC proto-oncogene, non-receptor tyrosine kinase Homo sapiens