Title : Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition.

Pub. Date : 2004 Jun

PMID : 15210853






1 Functional Relationships(s)
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1 A decrease in APE1 levels in siRNA-treated human osteogenic sarcoma cells led to enhanced cell sensitization to the DNA damaging agents: methyl methanesulfonate, H(2)O(2), ionizing radiation, and chemotherapeutic agents. Methyl Methanesulfonate apurinic/apyrimidinic endodeoxyribonuclease 1 Homo sapiens