Title : The HPV16 E6/E7 oncogene sensitizes human ovarian surface epithelial cells to low-dose but not high-dose 5-FU and 5-FUdR.

Pub. Date : 2004 Jul 16

PMID : 15207728






2 Functional Relationships(s)
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1 Molecular analysis indicates that induction of p53 and p21, and suppression of pRB are associated with apoptosis induced by 5-FUdR and may partly explain the hypersensitivity of E6E7/OSE cells to low-dose 5-FUdR. Floxuridine RB transcriptional corepressor 1 Homo sapiens
2 Molecular analysis indicates that induction of p53 and p21, and suppression of pRB are associated with apoptosis induced by 5-FUdR and may partly explain the hypersensitivity of E6E7/OSE cells to low-dose 5-FUdR. Floxuridine RB transcriptional corepressor 1 Homo sapiens