Title : Development of the proteasome inhibitor Velcade (Bortezomib).

Pub. Date : 2004

PMID : 15199612






1 Functional Relationships(s)
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1 The dipeptide boronic acid analogue VELCADE (Bortezomib; formerly known as PS-341, LDP-341 and MLM341) is a potent and selective inhibitor of the proteasome, a multicatalytic enzyme that mediates many cellular regulatory signals by degrading regulatory proteins or their inhibitors. Boronic Acids carboxypeptidase Q Homo sapiens