Title : Nongenomic effects of 17beta-estradiol in human platelets: potentiation of thrombin-induced aggregation through estrogen receptor beta and Src kinase.

Pub. Date : 2005 Jan 1

PMID : 15198955






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 17beta-estradiol caused the rapid phosphorylation of the tyrosine kinases Src and Pyk2 and the formation of a signaling complex, which included Src, Pyk2, and the phosphatidylinositol 3-kinase. Estradiol protein tyrosine kinase 2 beta Homo sapiens
2 17beta-estradiol caused the rapid phosphorylation of the tyrosine kinases Src and Pyk2 and the formation of a signaling complex, which included Src, Pyk2, and the phosphatidylinositol 3-kinase. Estradiol protein tyrosine kinase 2 beta Homo sapiens
3 On treatment with 17beta-estradiol, Src and Pyk2 activation occurred in the membrane fraction but not in the cytosol. Estradiol protein tyrosine kinase 2 beta Homo sapiens