Title : Differential expression of cytochrome P450 isoforms in the lungs of septic animals.

Pub. Date : 2004 May

PMID : 15190971






2 Functional Relationships(s)
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1 Since CYP2C11 and CYP2J4 convert arachidonic acid to vasodilative epoxyeicosatrienoic acids, and CYP4A3 metabolizes arachidonic acid to both epoxyeicosatrienoic acids and vasoconstrictive 19,20-hydroxyeicosatetraenoic acid, the aim of this study was to examine the expression of these isoforms in sepsis and their association with hemodynamic changes. epoxyeicosatrienoic acids cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus
2 Since CYP2C11 and CYP2J4 convert arachidonic acid to vasodilative epoxyeicosatrienoic acids, and CYP4A3 metabolizes arachidonic acid to both epoxyeicosatrienoic acids and vasoconstrictive 19,20-hydroxyeicosatetraenoic acid, the aim of this study was to examine the expression of these isoforms in sepsis and their association with hemodynamic changes. epoxyeicosatrienoic acids cytochrome P450, subfamily 2, polypeptide 11 Rattus norvegicus