Title : Cyclooxygenase-1-dependent prostaglandin synthesis modulates tumor necrosis factor-alpha secretion in lipopolysaccharide-challenged murine resident peritoneal macrophages.

Pub. Date : 2004 Aug 13

PMID : 15181007






1 Functional Relationships(s)
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1 These results demonstrate autocrine regulation of TNF-alpha secretion by endogenous PGs synthesized primarily by COX-1 in RPM and suggest that COX-1 may play a significant role in the regulation of the early response to endotoxemia. Phosphatidylglycerols tumor necrosis factor Mus musculus