Title : Relationship of plasma extracellular-superoxide dismutase level with insulin resistance in type 2 diabetic patients.

Pub. Date : 2004 Jun

PMID : 15171689






3 Functional Relationships(s)
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1 Administration of pioglitazone to 19 diabetic patients significantly increased the plasma levels of EC-SOD (69.9+/-19.3 ng/ml to 97.4+/-25.9 ng/ml; P < 0.0001) and adiponectin, while it decreased tumor necrosis factor-alpha (TNF-alpha). Pioglitazone superoxide dismutase 3 Homo sapiens
2 It is possible that the increase in the EC-SOD level by pioglitazone administration in diabetic patients is due to a decline of TNF-alpha, which is known to suppress EC-SOD expression. Pioglitazone superoxide dismutase 3 Homo sapiens
3 It is possible that the increase in the EC-SOD level by pioglitazone administration in diabetic patients is due to a decline of TNF-alpha, which is known to suppress EC-SOD expression. Pioglitazone superoxide dismutase 3 Homo sapiens