Title : Negative regulation of the protein kinase C activator-induced ICAM-1 expression in the human bronchial epithelial cell line NCI-H292 by p44/42 mitogen-activated protein kinase.

Pub. Date : 2004 Jun 11

PMID : 15147830






3 Functional Relationships(s)
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Protein Name
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1 The MEK inhibitor U0126 (0.1 to 10 microM) enhanced the TPA-induced ICAM-1 expression but not the IFN-gamma-induced one. Tetradecanoylphorbol Acetate intercellular adhesion molecule 1 Homo sapiens
2 Furthermore, PD98059 (0.5 to 50 microM), another MEK inhibitor, enhanced the TPA-induced ICAM-1 expression as well. Tetradecanoylphorbol Acetate intercellular adhesion molecule 1 Homo sapiens
3 BAY11-7082, an inhibitor of nuclear factor kappaB (NF-kappaB) activation, and MG132, a 26S proteasome inhibitor, reduced the TPA-induced ICAM-1 expression but not the IFN-gamma-induced one. Tetradecanoylphorbol Acetate intercellular adhesion molecule 1 Homo sapiens