Title : Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study.

Pub. Date : 2004 Jul 1

PMID : 15122597






1 Functional Relationships(s)
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1 Although compound homozygous variants at cSHMT and MTHFD1 loci had the lowest plasma folate levels compared to other compound genotypes, no significant gene-gene interactions were observed. Folic Acid methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 Homo sapiens