Title : Gamma-interferon inhibits extracellular matrix synthesis and remodeling in collagen lattice cultures of normal and scleroderma skin fibroblasts.

Pub. Date : 1992 Apr

PMID : 1511700






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 This study shows that IFN-gamma regulates cell behavior in three-dimensional collagen matrices: (i) it decreases protein and specifically glycosaminoglycan synthesis in scleroderma fibroblasts, (ii) it modulates the interactions between cells and matrix that lead to the retraction of the lattice. Glycosaminoglycans interferon gamma Homo sapiens