Title : Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists.

Pub. Date : 2004

PMID : 15111235






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RA/TPA treated cells exhibited the highest levels of tyrosine hydroxylase and DAT but lower levels of vesicular monoamine transporter. Tetradecanoylphorbol Acetate solute carrier family 6 member 3 Homo sapiens
2 RA/TPA differentiated cells evidenced high sensitivity to the neurotoxic effects of MPP+ (0.03 to 3.0 mM), and the neurotoxic effects of MPP+ were blocked with the DAT inhibitor 1-(2-[bis(4-fluorophenyl)methoxy]ethyl)-4-(3-phenylpropyl)piperazine (GBR 12909). Tetradecanoylphorbol Acetate solute carrier family 6 member 3 Homo sapiens