Title : Role of thiocyanate, bromide and hypobromous acid in hydrogen peroxide-induced apoptosis.

Pub. Date : 2004 Feb

PMID : 15104210






3 Functional Relationships(s)
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1 We conclude that the physiologic concentrations of thiocyanate found in human plasma could modulate the cytototoxicity of H2O2 and its resulting highly toxic MPO-generated hypochlorous acid by competing with chloride for MPO. thiocyanate myeloperoxidase Homo sapiens
2 We conclude that the physiologic concentrations of thiocyanate found in human plasma could modulate the cytototoxicity of H2O2 and its resulting highly toxic MPO-generated hypochlorous acid by competing with chloride for MPO. thiocyanate myeloperoxidase Homo sapiens
3 Furthermore, the oxidative products of the reaction of thiocyanate with MPO are relatively innocuous for human leukemic cells in culture. thiocyanate myeloperoxidase Homo sapiens