Title : Covalent and noncovalent chemical modifications of arginine residues decrease dopamine transporter activity.

Pub. Date : 2004 Jun 15

PMID : 15103693






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The tropane-based DAT inhibitors cocaine, WIN 35065-2, and WIN 35428 also attenuated the effects of PG. Cocaine solute carrier family 6 member 3 Rattus norvegicus
2 Thus, Arg residues are important for DAT activity and the results suggest that DA and cocaine both interact with Arg residues. Cocaine solute carrier family 6 member 3 Rattus norvegicus
3 DA and cocaine may interact with the same functionally important Arg residue at the DAT, and 2). Cocaine solute carrier family 6 member 3 Rattus norvegicus