Title : A role of reactive oxygen species in apoptotic activation of volume-sensitive Cl(-) channel.

Pub. Date : 2004 Apr 27

PMID : 15096609






1 Functional Relationships(s)
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1 Thus, it is concluded that an apoptosis-triggering anion conductance is carried by the volume-sensitive outwardly rectifying Cl(-) channel and that the channel activation on apoptotic stimulation with staurosporine, but not with Fas ligand or TNF-alpha, is mediated by ROS. Staurosporine tumor necrosis factor Homo sapiens