Title : Prenatal androgens alter GABAergic drive to gonadotropin-releasing hormone neurons: implications for a common fertility disorder.

Pub. Date : 2004 May 4

PMID : 15096602






2 Functional Relationships(s)
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1 GnRH neurons receive a major input from gamma-aminobutyric acid (GABA)ergic neurons, and GABA type A receptor activation may play a role in their regulation by steroids. Steroids gonadotropin releasing hormone 1 Mus musculus
2 The ability of prenatal steroid exposure to initiate changes that alter functional inputs to GnRH neurons in adults has important implications for understanding the regulation of normal reproduction as well as the hypothalamic abnormalities of fertility disorders. Steroids gonadotropin releasing hormone 1 Mus musculus