Title : [In vitro reactivation of acetylcholinesterase inhibition by O-isopropylmethylfluorophosphonate using the bisquarternary oxime, HS-6].

Pub. Date : 2004 Mar

PMID : 15095579






2 Functional Relationships(s)
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1 The ability of the oxime HS-6 [1-(4-hydroxyiminomethylpyridinium)-3-(4-carbamoylpyridinium)-2-oxa-propane dichloride] to reactive in vitro the enzyme acetylcholinesterase inhibited by the nerve agent sarin [O-isopropylmethylfluorophosphonate] was evaluated. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens
2 The oxime HS-6 was an effective reactivator of sarin-inhibited AChE. Oximes acetylcholinesterase (Cartwright blood group) Homo sapiens