Pub. Date : 2004 May 1
PMID : 15095415
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We report that curcumin prevented PDT-induced JNK activation, mitochondrial release of cytochrome c, caspase-3 activation, and cleavage of PAK2. | Curcumin | mitogen-activated protein kinase 8 | Homo sapiens |
2 | Collectively, these results demonstrate that singlet oxygen triggers JNK activation, cytochrome c release, caspase activation and subsequent apoptotic biochemical changes during PDT and show that curcumin is a potent inhibitor for this process. | Curcumin | mitogen-activated protein kinase 8 | Homo sapiens |