Pub. Date : 2004 May 14
PMID : 15094324
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Agonists of the vanilloid receptor type 1 (VR1), such as capsaicin, induce an analgesic effect following an initial excitatory response. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
| 2 | This prolongation of capsaicin-induced analgesia during inflammation was mediated through VR1 since it was completely blocked by coadministration of capsazepine (10 microg). | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
| 3 | Overall, these results show that the analgesic effects of capsaicin are importantly enhanced during inflammation, supporting the fact that the stimulation of VR1 could perhaps constitute a suitable strategy to avoid inflammatory hyperalgesia. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |