Title : Abrogation of cisplatin-induced hepatotoxicity in mice by xanthorrhizol is related to its effect on the regulation of gene transcription.

Pub. Date : 2004 May 1

PMID : 15094305






2 Functional Relationships(s)
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1 In conclusion, the ability of xanthorrhizol to regulate the DNA-binding activities of transcription factors, NF-kappaB and AP-1, could be one possible mechanism to elucidate the preventive effect of xanthorrhizol on cisplatin-induced hepatotoxicity. xanthorrhizol jun proto-oncogene Mus musculus
2 In conclusion, the ability of xanthorrhizol to regulate the DNA-binding activities of transcription factors, NF-kappaB and AP-1, could be one possible mechanism to elucidate the preventive effect of xanthorrhizol on cisplatin-induced hepatotoxicity. xanthorrhizol jun proto-oncogene Mus musculus