Title : Par-4 inhibits choline uptake by interacting with CHT1 and reducing its incorporation on the plasma membrane.

Pub. Date : 2004 Jul 2

PMID : 15090548






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CHT1 is a Na(+)- and Cl(-)-dependent, hemicholinium-3 (HC-3)-sensitive, high affinity choline transporter. Hemicholinium 3 solute carrier family 5 member 7 Homo sapiens
2 CHT1 is a Na(+)- and Cl(-)-dependent, hemicholinium-3 (HC-3)-sensitive, high affinity choline transporter. Hemicholinium 3 solute carrier family 5 member 7 Homo sapiens
3 Transfection of neural IMR-32 cells with human CHT1 conferred Na(+)-dependent, HC-3-sensitive choline uptake that was effectively inhibited by cotransfection of Par-4. Hemicholinium 3 solute carrier family 5 member 7 Homo sapiens