Title : Constitutively activated phosphatidylinositol 3-kinase primes platelets from patients with chronic myelogenous leukemia for thrombopoietin-induced aggregation.

Pub. Date : 2004 Jun

PMID : 15085152






1 Functional Relationships(s)
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1 Pretreatment with PI3-kinase inhibitors (wortmannin and LY294002) dose-dependently inhibited TPO-induced aggregation of CML-CP platelets. Wortmannin thrombopoietin Homo sapiens