Title : Roles of endogenous prostaglandins and cyclooxygenase izoenzymes in mucosal defense of inflamed rat stomach.

Pub. Date : 2004 Mar

PMID : 15082878






2 Functional Relationships(s)
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1 Endogenous prostaglandins (PGs) are involved in adaptive gastric protection against acute injury, and cyclooxygenase (COX)-1 is responsible for the production of PGs in this phenomenon. Prostaglandins cytochrome c oxidase I, mitochondrial Rattus norvegicus
2 These results suggest that endogenous PGs derived from both COX-1 and COX-2 are involved in the mucosal defense of the inflamed stomach, partly by decreasing acid secretion and contribute to maintaining the mucosal integrity under such conditions. Prostaglandins cytochrome c oxidase I, mitochondrial Rattus norvegicus