Title : Simultaneous determination of dexamethasone and 6 beta-hydroxydexamethasone in urine using solid-phase extraction and liquid chromatography: applications to in vivo measurement of cytochrome P450 3A4 activity.

Pub. Date : 2004 May 25

PMID : 15081938






1 Functional Relationships(s)
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1 So, the 6 beta-hydroxydexamethasone/dexamethasone urinary ratio could be a specific marker for human CYP3A4 activity. Dexamethasone cytochrome P450 family 3 subfamily A member 4 Homo sapiens